GENERIC NAME: GUANETHIDINE - ORAL (gwan-ETH-eh-deen)
BRAND NAME(S): Ismelin
Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage | Medical Alert
WARNING: This medication can frequently cause dizziness and weakness which may lead to fainting, especially when first starting this medication. Symptoms occur more often upon awakening and may increase during hot weather, exercise, or when drinking alcohol. To avoid fainting do not stand quickly and avoid standing or exercising for long periods of time.
USES: This medication relaxes and expands blood vessels and is used to treat high blood pressure (hypertension).
HOW TO USE: Take this medication exactly as prescribed. Try to take it at the same time(s) each day. Take with food or milk to avoid stomach irritation. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick.
SIDE EFFECTS: Dizziness, drowsiness, headache, diarrhea, sexual problems in males, loss of appetite, fatigue, and nasal congestion may occur as your body adjusts to the medication. Inform your doctor promptly if you develop: chest pain, shortness of breath, skin rash, swelling of the hands or feet, yellowing of the eyes or skin, severe diarrhea, fainting, muscle aches. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: Before taking guanethidine, tell your doctor if you have: heart or blood vessel disease, liver or kidney disease, stomach ulcers, diarrhea, asthma, fever, pheochromocytoma, diabetes. To avoid dizziness and lightheadedness when rising from a seated or lying position, change positions slowly. Avoid prolonged standing and be careful on stairs. Limit your intake of alcoholic beverages while taking this medication. Alcohol can lead to excessive drowsiness or fainting. Also avoid hot showers, saunas, or prolonged exercise as excessive heat can worsen dizziness. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known if guanethidine passes into breast milk. Consult with your doctor before breast-feeding.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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